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I had my genome sequenced!

Siro

Siro

Well-Known Member
Contributor
2018 Award Winner
How exciting. I am currently going through the troves of data. It doesn't seem like I have anything that serious.




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bro i recently found out about this site and was thnking about doing it.
it's $99. worth it? tell us ur experiences, review, etc. please bro i would appreciate it!
 
HeavenHarris said:
bro i recently found out about this site and was thnking about doing it.
it's $99. worth it? tell us ur experiences, review, etc. please bro i would appreciate it!
Click to expand...

It took about 6 weeks to get my results. They accurately predicted my traits, with one possible exception. They insist I'm lactose intolerant. I don't think I am, but upon reading other comments on the website, a lot of people who did not know they were intolerant found that out through the test. I have had bad acid reflux for a few years now, and I may have noticed a correlation with dairy consumption. I will have to test it more thoroughly. Or have it tested professionally.

They're also reconstructing my ancestry, which is pretty fun. It'll take a few more days to get the full picture, but so far it's been fun tracing my genetic history across the planet (I'm 2.2% neanderthal).

They have an astounding amount of information on plenty of genetic markers, but it's all relative to the average.

The process was incredibly cheap and painless, and I'd totally recommend it for anyone who's thinking about it. What is there to lose?

Let me know if you have any specific questions.
 
How legit is it?
I mean isn't it some sort of express DNA test by a machine with "it appears you are ok" results or it's a full scale analysis done as if you come to a lab to get tested for something specific?
 
So how huge was your gay gene?





kidding of course
 
zbone said:
How legit is it?
I mean isn't it some sort of express DNA test by a machine with "it appears you are ok" results or it's a full scale analysis done as if you come to a lab to get tested for something specific?
Click to expand...

It is not a DNA test like the ones used on day-time reality-TV. It's a genome sequence. More specifically, it's an exome sequence. It only gives you the protein coding part of the genome, since that's the part that's fairly well understood.

It should be able to determine any known genetic defects and the like, but I know some genes are patented, and I don't know how the system works exactly.

So in short, it is just like a full scale lab test. But keep in mind just how young the entire field is. It is for educational purposes only.
 
Warning. Cy did this once as well .. and his talking about it here earned him an infraction.
 
This is way awesome... I have been talking with my wife about getting our genomes sequenced... I'm for sure going to get this for my bday !!!
 
Keep in mind that sequencing using both Single Nucleotide Polymoprhisms and Short Tandem Repeats isn't as accurate as you'd think. Whole Genome Sequencing is in a completely other echelon than STR analysis, as using relativism with short polymorphisms definitely has its limitations.

Significant SNP disadvantages
Several significant disadvantages exist with SNP markers when considered as a possible replacement for currently used STR loci with the top two being the number of loci needed and the inability to easily decipher mixtures. First, because SNPs are not as polymorphic as STRs, more SNPs are required to reach equivalent powers of discrimination or random match probabilities. Numbers on the order of 40–60 SNPs have been suggested in order to approximate the power of 13–15 STR loci as are commonly in use today [10, 12, 19].
Remember that 15 STRs can be routinely amplified simultaneously in a single multiplex amplification reaction from minimal amounts (e.g., 500 pg) of DNA template using commercially available kits such as PowerPlex 16 and Identifiler. While multiplex PCR amplification of such a large number of SNPs (e.g., *50) has only recently been demonstrated in a research setting [14], routine production and commercialization of robust assays containing upwards of 100 oligonucleotide PCR primers will not be trivial. Likewise, the expense of examining more loci will be higher.
Perhaps more importantly data interpretation becomes increasingly difficult with more loci and amplification products. Issues with locus drop out will become more significant when three to five times more loci are involved in comparison to traditional STR typing. In addition, assays with a larger number of loci are more sensitive to the quantity and integrity of the input DNA template particu- larly when trying to amplify limited DNA materials.
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https://www.cstl.nist.gov/strbase/pub_pres/FSMP_STRs_vs_SNPs.pdf


Still cool though Siromar!!
 
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