Definitely. I don't know if 220 will be his eventual playing weight, but that is 15 lbs heavier than even the big point guards like Westbrook, Dwill, and Rose. He would be a bowling ball down the lane. There's really no comparison you can draw up for Smart, he is a unique player.
Well, physically you can point to Stuckey and Baron Davis, but it's hard to come up with a direct comp.