Tupac. He was prolific. Who knows what he could have gone on to.
I would add Charles Mingus to Coltrane and Miles Davis.
Have to add Robert Johnson. Armstrong as well.
Then goes with
Jimi Hendrix
Thelonius Monk
Muddy Waters
Ella Fitzgerald
Chet Baker
How you could possibly go 4 pages into this discussion without mentioning Prince amazes me. Here, just check out this guitar solo (starting around 3:20 in the video)
https://www.youtube.com/watch?v=6SFNW5F8K9Y
I came here for one reason, and one reason only. This list starts with Nickelback. It can end anywhere else you please, but that is where it begins.