The Irrational Covid

[babe]

A whole shipload of research I know nothing about....

Frontiers | Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System

The amount of erythrocyte-derived microRNA (miRNA) represents the majority of miRNA expression in whole blood. miR-451, miR-144, and miR-486, which are abund...

www.frontiersin.org

Looks like a promising field for a lot more research.

The answer to the question above is YES. Very YES. We have hardly begun to understand blood cells generally.

Yes, the RBC and lymphocytes are players in micro (relatively small) RNA, which appear to have many and important roles in health and pathology of disease and disorders.

In general, mRNA (messenger RNA generally from mitochrondria (extranuclear, outside the nucleus) are protein manufacturing templates. The micro species discussed here are probably shorter. amd may act as signals/modifiers directly or through short protein products.

Unless there is something that especially precludes the vaccine delivery vehicle from tagging an erythrocyte, we should figure it probably does happen, and an RBC will take in the mRNA template and produce an antigen like other cells. Lysis is the usual end, the way the antigen gets out into the system.

 

[One Brow]

Are RBC and white cells really lacking in microsomes(the machinery you mention above?)

I referred to red blood cells and platelets, not white blood cells, and I believe the structure you meant to say is a ribosome, which is the structure that converts RNA into proteins, IIRC.

Most red blood cells don't have ribosomes. Lacking a nucleus and a need to construct proteins, they don't need them.

Platelets do not have nuclei, but do have ribosomes, and can generate a much smaller range of proteins. Perhaps the virus can adversely affect them, but I don't think they can generate more viruses, and the vaccine doesn't doesn't have enough material to affect that many platelets to that degree.

 

[babe]

For any serious student of vaccines, here's a readable article that appears to be up there in respectability and facts:

AAAS

blogs.sciencemag.org

So I learned that MVP is right, and that I was right, too. Well borderline maybe. MVP might actually be in this field of study. There are two strategies that come together at the point of using monoclonal mRNA to produce the spike protein of Covid19. The spike is about all any contacting cell will likely "see" and recognize as an antigen and create antibodies to.

The AstraZeneca and J&J use another virus as the carrier of the gene, using gene-splicing to put the spike-coding DNA into patient cell where the patient makes the mRNA. Some others also. The Pfizer and Moderna don't use the virus but create another carrier into the cell, and I think emplace mRNA directly. Neither uses a Covid19 virus either dead or attenuated to get the spike synthesis going in the patient.

 

[babe]

I referred to red blood cells and platelets, not white blood cells, and I believe the structure you meant to say is a ribosome, which is the structure that converts RNA into proteins, IIRC.

Most red blood cells don't have ribosomes. Lacking a nucleus and a need to construct proteins, they don't need them.

Platelets do not have nuclei, but do have ribosomes, and can generate a much smaller range of proteins. Perhaps the virus can adversely affect them, but I don't think they can generate more viruses, and the vaccine doesn't doesn't have enough material to affect that many platelets to that degree.

Let's correct me here. yes, microsomes are cell lysis debris, with remnants of the endoplasmic reticulum, liposomes less complicated are lipid bubbles, which can be carriers of other stuff sometimes, I think. ribosomes are the extranuclear factories where RNA stuff is made in spades. R as in ribose Ribonucleic acids ,RNA, outside the nucleus.. and RNA is the template for proteins generally. microsomes are what you find in the lab when you break cells. More than just lipids or oils, they generally have other stuff too.

I think the article I linked above states that although there is no nucleus there are ribosomes. I still have not processed that article. This is an exercise for me. I will revisit that article and do some more thinking and some more searching.

Amazing article. I think it goes into how RBC miRNAs might be involved in cancer, and could be tested for as a marker for some cancers. Literally hundreds of miRNA species.

It looks like your skepticism regarding my idea of blood clotting coming from vaccine acting in the RBC and platelets is more sensible.

 

[Jazz4ever]

If I could ask Fauci one question it would be: what is the plan to ever stop wearing masks? In this hearing with Rand Paul. he cites current vaccines offer little to no protection against the 351 variant. There is always going to be another variant as years go on - it's what viruses do. By the time an updated vaccine comes out to protect against 351 variant, a new strain will have emerged and thus we restart the process over and over just like the flu.

 

[babe]

If I could ask Fauci one question it would be: what is the plan to ever stop wearing masks? In this hearing with Rand Paul. he cites current vaccines offer little to no protection against the 351 variant. There is always going to be another variant as years go on - it's what viruses do. By the time an updated vaccine comes out to protect against 351 variant, a new strain will have emerged and thus we restart the process over and over just like the flu.

If I could ask Fauci one question it would be: what is the plan to ever stop wearing masks? In this hearing with Rand Paul. he cites current vaccines offer little to no protection against the 351 variant. There is always going to be another variant as years go on - it's what viruses do. By the time an updated vaccine comes out to protect against 351 variant, a new strain will have emerged and thus we restart the process over and over just like the flu.

Fauci wants us to wear masks for variants that aren't here yet, or that have not developed yet.

Masks primarily are effective in preventing spread because they catch virus from the mask wearer. That is always a good thing, of course. But if you have had the vaccine or the virus the benefit is close to zero, for the mask wearer as well as others. Fauci has admitted the fact that a study shows a distance of 3 ft shows the same b benefit as 6ft. with no masks in use. A mask if it's on right and does filter all the exhaled breath actually means, likely, that 1 ft distance is good enough. Most cheap masks allow lateral air escapage, but in such cases a distance of 3 ft would still be adequate. Measures like good hygiene such as flushing sneeze tissues down a toilet and replacing masks or washing them every several hours, hand washing, frequent disinfection of common surfaces, with respect for distancing seems adequatge to open schools.

And businesses.

And for good measure, for hell's sake, install electrostatic and HEPA filters and ozone generators in duct work. Ozone is a very efficient disinfectant, is short-lived and is tolerated by humans at very effective disinfection levels. The government paid for the damn study. They know this.

tyrants just love tove to give us stupid orders.

We've been Fauci'd.

 

[babe]

If I could ask Fauci one question it would be: what is the plan to ever stop wearing masks? In this hearing with Rand Paul. he cites current vaccines offer little to no protection against the 351 variant. There is always going to be another variant as years go on - it's what viruses do. By the time an updated vaccine comes out to protect against 351 variant, a new strain will have emerged and thus we restart the process over and over just like the flu.

Second point. Almost all variants we have seen so far are stopped by vaccines or wild-type original infections with any of the several early lines of virus.

Re-infection rates are nearly zero, 1 in a million or so. The antibodies appear to be long-lived in humans with no evidence of declines within our experience so far.

Florida's policy of emphasizing protection/attention on most vulnerable population segments appears to be successful.

So we have a virus that practically has no effect on nearly 90% of us, and most of those 10% can be identified and specifically protected. We now have adequate hospital capacity for those who need care, and several very good treatment protocols, including antibody-loaded plasma infusion and some fairly good antivirals, and other measures to counteract severe reaction like the cytokine storm.

If the virus were some damn Bill Gates wet dream for world depopulation, he sure picked a loser virus. Either that or Trump outsmarted Gates.

But hey, there is still that Darwin theory about the survival of those who use the good sense God gives us all.

The mask is probably worth wearing in any crowd just because you won't get something from a passerby spitting in the wind. Oh, say, like the flu.

and, uhhhmmmm, I don't want that South African variant either.

 

[babe]

I referred to red blood cells and platelets, not white blood cells, and I believe the structure you meant to say is a ribosome, which is the structure that converts RNA into proteins, IIRC.

Most red blood cells don't have ribosomes. Lacking a nucleus and a need to construct proteins, they don't need them.

Platelets do not have nuclei, but do have ribosomes, and can generate a much smaller range of proteins. Perhaps the virus can adversely affect them, but I don't think they can generate more viruses, and the vaccine doesn't doesn't have enough material to affect that many platelets to that degree.

I still need to review the basics here. Pretty sure all cells from a stem cell line have some sort of remnant of all the stem capacities. Pretty sure no cell is entirely without extranuclear ribosome capacities.

What I'm chewing on here is this. The study I linked appears to be Nobel-Prize level groundbreaking. It looks like it is the beachhead into a whole new world of study. I mean mad cow disease, prion-class proteings, and stuff that causes dementia and cancer, maybe a deep residual reserve of cancer-fighting naturals.

And these MiRNAs are made inside the erythrocyte, in spades.

 

[Jazz4ever]

Fauci wants us to wear masks for variants that aren't here yet, or that have not developed yet.

Masks primarily are effective in preventing spread because they catch virus from the mask wearer. That is always a good thing, of course. But if you have had the vaccine or the virus the benefit is close to zero, for the mask wearer as well as others. Fauci has admitted the fact that a study shows a distance of 3 ft shows the same b benefit as 6ft. with no masks in use. A mask if it's on right and does filter all the exhaled breath actually means, likely, that 1 ft distance is good enough. Most cheap masks allow lateral air escapage, but in such cases a distance of 3 ft would still be adequate. Measures like good hygiene such as flushing sneeze tissues down a toilet and replacing masks or washing them every several hours, hand washing, frequent disinfection of common surfaces, with respect for distancing seems adequatge to open schools.

And businesses.

And for good measure, for hell's sake, install electrostatic and HEPA filters and ozone generators in duct work. Ozone is a very efficient disinfectant, is short-lived and is tolerated by humans at very effective disinfection levels. The government paid for the damn study. They know this.

tyrants just love tove to give us stupid orders.

We've been Fauci'd.

I would like to have a look at Mr. Fauci's and some of his family/associates stock portfolios. My guess is MRNA and JNJ are holdings.

 

[babe]

I would like to have a look at Mr. Fauci's and some of his family/associates stock portfolios. My guess is MRNA and JNJ are holdings.

The rumors are out there, for sure.

I'm noting that actually all of the vaccines involved patients' cell-produced antigen, and hence, cell lysis of whatever cell takes in the carrier. What I wonder most about in the long-term is we have no measure of the risk that the antigens so produced might over time become tagged as "self" and not only stop working at all, but maybe even tag other host issues and produce autoimmune disease.

 

[One Brow]

I would like to have a look at Mr. Fauci's and some of his family/associates stock portfolios. My guess is MRNA and JNJ are holdings.

I suppose you can always just assume that whatever supports your beliefs happens to be true.

Or, you can search for truths even when they make you uncomfortable.

 

[gandalfe]

If I could ask Fauci one question it would be: what is the plan to ever stop wearing masks? In this hearing with Rand Paul. he cites current vaccines offer little to no protection against the 351 variant. There is always going to be another variant as years go on - it's what viruses do. By the time an updated vaccine comes out to protect against 351 variant, a new strain will have emerged and thus we restart the process over and over just like the flu.

Viruses mutate when they copy themselves - minor errors in the copy may create a more or less deadly/transmissible/severe virus. Any new variant that is less of any of those things is something that we don't worry about (well, I guess unless it's also more difficult to treat, or if we ignore it to much and it starts spreading more, and then starts mutating as it spreads more...) So if you can slow the spread down, you slow the number of new variants, which then gives you more time to prepare for new variants, which slows the spread even more, etc, etc.

I'm not a scientist, but I can at least apply some critical thinking to the subject.