You make a lot of assumptions about what other people consume and in what quantities.
Rational CoViD-19 Discussion Thread: Science vs. Politics
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You're ignoring the patent process. If the protocol worked, one of the big Pharma companies cold patent a combination of HCQ and some other drug that had not been patented before. While hospitals might not buy it, they could sell it to pharmacies and get doctors to prescribe it, then cash in. They do this all the time with medications whose patents are about to expire.
I don’t think this setting by lends very well to this strategy, though, as the combo would have to have an FDA indication (or the two individually would need indications, like with Janumet or lisinopril-HCTZ) and all the other combo meds make money because they’re chronic meds. But for every Janumet and lisinopril-HCTZ, you’ve got dumbass meds like Symbyax (which I question if anyone has ever really prescribed). Of course, perhaps in a primary care realm where there are so many meds that you may not look at cost as much those things can be prescribed more frequently (relatively), but often the insurance is going to spit it back and require a prior authorization, or the patient calls from the pharmacy when they find out it’s going to cost $300.
The real money is in unique medications. And chronic meds. There’s no money in short-duration meds, which is why you don’t see a ton of development in antibiotics relative to everything else.
I assume nothing.
what I do is try to tease some of the JFC folks who need to learn to laugh at themselves, just a little.
I made a science project outta brewing alcohol once upon a time, and then distilled it. I have always used absolute ethanol when called for in my lab procedure. You know, the stuff that comes with the Utah State tax seal. My most revered great grandfather did some fine wines from grapes, and one of my other great grandfathers, and several generations before him, kept a fine pub in London, about a block from Parliament, that was known as the Pub. As in the place.
I love grapes, and grape juice. I have developed my own variety of concord grapes that does well in Salt Lake City. I can't eat them all, some get pretty ripe. Like in December, I'm still picking grapes off the vines, whuile the leaves are almost completely brown and gone. I think they get about as good as beer.
Who knows, maybe I'll develop my own little niche brewery. Pretty sure Jesus didn't drink orange juice.
But to your point, there was a bit of chatter between two or three of the JFC folks, and it has long been know that you sometimes do a brew of your own.
Someone, at the outbreak of the Covid Panic, remarked to Fish to be careful not to drink too much. Now, as a matter of fact, for all I know, Fish is a Mormon choir boy who has never tasted a drop of alcohol, and who never will. But when the subject is how to be safe from Covid, or other Corona viruses, what is known is that they have, under their glycoproteind arms, a lipid membrane, almost like a cell has, and the glycoprotein arm has a little hook at the end, sorta nestled iin a shallow cup of more stable protein, of some lipophilic amino acids. Because of the lipid surfaces, Corona viruses generally have pretty good "binding coefficients", meaning they stick pretty tightd to cell membranes, and sorta suck themselves inside by rearranging the cell membrane around the virus.
Alcohol, at stdrengths good enough to affect a neuron, will kill a corona virus...…. Not entirely sure just what that graph would look like, but pretty sure it would be on that scale. So people who dreink pretty good might be protecting themselves from Covid.
I have not done the experiment in a research setting, so this is just anecdotal, OK.
My father used to swear by the antiviral properties of red grapes. So do I.
I believe that our statistics for THE GREAT COVID PANIC of 2020, Americans, while staying at home took up drinking alcohol, almost doubled the normal consumption. And it is my understanding that all my friends in California were delighted with my advice. Do a well-chlorinarted Jacussi session three times a day, with plenty of wine.
We should do a study to see if heavy drinkers still caught Covid, I suppose.
Until then, please understand that I love to tell stories, and all my evidence is anecdotal, and I sincerely believed some good drinking would wash the Covid down almost as good as soap, while tasting a whole lot better.
In my experience, I have learned to ignore the patent process. When you're trying to fly a kite, stay away from the airport takeoff/landing areas just off the runway. A small business lacking the moolah to hire a top tier law firm to defend a patent, is often better off flying low, off the radar, and way outta the way of the big birds.
If you don't have such legal help, and the moolah it takes to feed them, a patent is virtually an advertisement that reads something like..... Here's a gold mine. Just kick me, and it's yours.
In my own mind, I was looking at HCQ as a remedy that has been patented, somewhere, sometime, across 100 years or so, for every malady ever imagined by our most dedicated hypochondriacs across five generations.....
Besides, it is about as simple as aspirin, maybe even easier to make. You could look it up in Beilstein. Pretty sure the German chemists have several synthesis schema, involving about two steps from benzene. But why the hell even start there, lots of better starting points refined outta crude oil by the ton, or practically the price of diesel fuel or jet fuel
I thjink it would be one step if you started with vanilla.
It takes years to get a patent approved. I don't think anyone wants to do that.
Of course.
Here's the latest Covid charts from Worldometer. Pretty sure the data is being distorted on purpose now. Way too slow calling a patient recovered, way too heavy calling the symptoms "Covid", and labeling deaths as due to Covid.
I think the reality is now that we have, the world over, about half the active cases, and about half the deaths properly attributed.
I mean, I really get tired of being worked about something when it takes abject falsification to make the case.
But who the hell am I?
https://www.worldometers.info/coronavirus/
OK. Here's my reasoning. Most infective carriers of Covid have a run of maybe ten days being capable of passing the virus, less than 14 is pretty much 99% of the cases. Given it takes about two or three days to establish itself in any noticeable degree, and that a good immune defense will show up a few days later, and the illness is almost always over in two weeks, except for the ARDS subset... Most of them, 80%, die in f few days even on the breathing assistance.
This site isn't calling a case "closed" until a month is run, unless the patient dies. The US doctors are required to report every case with any sign of Covid, a covid death. I mean, you're rushed to the hospital with a heart attack and die with the defibrillator, but you had a temp of 101 F. Damnit, it was Covid that caused it all.
Somehow, also, the flu season ended suddenly this year when we discovered the new virus. No more flu deaths since Feb. 1. Do me a favor. look it up.
I think the reality is now that we have, the world over, about half the active cases, and about half the deaths properly attributed.
I mean, I really get tired of being worked about something when it takes abject falsification to make the case.
But who the hell am I?
https://www.worldometers.info/coronavirus/
OK. Here's my reasoning. Most infective carriers of Covid have a run of maybe ten days being capable of passing the virus, less than 14 is pretty much 99% of the cases. Given it takes about two or three days to establish itself in any noticeable degree, and that a good immune defense will show up a few days later, and the illness is almost always over in two weeks, except for the ARDS subset... Most of them, 80%, die in f few days even on the breathing assistance.
This site isn't calling a case "closed" until a month is run, unless the patient dies. The US doctors are required to report every case with any sign of Covid, a covid death. I mean, you're rushed to the hospital with a heart attack and die with the defibrillator, but you had a temp of 101 F. Damnit, it was Covid that caused it all.
Somehow, also, the flu season ended suddenly this year when we discovered the new virus. No more flu deaths since Feb. 1. Do me a favor. look it up.
Worldwide, the deaths reported today are approximately the same as those reported March 6, under 4K.
Worldwide, the new cases reported today are approximately the same as those reported March 30, around 70k. With a lot of tests being done, not just symptomatic diagnoses.
Speaking of testing, in the USA during testing, the positive antigen (sick) stat is running about 0.1%, or one in a thousand tests where there is no symptoms. This is now our %infective rate in the general population...…. Today, I saw a lot of people with masks walking along the streets. My wife says she's got one for me. I got one from my doctor. So here you are, in Utah, walking along a practically empty street, wearing your mask, encountering oh,maybe five people each block. You'd have to walk 200 blocks, or 33 miles on average, to pass one covid positive person.....
Worldwide, the new cases reported today are approximately the same as those reported March 30, around 70k. With a lot of tests being done, not just symptomatic diagnoses.
Speaking of testing, in the USA during testing, the positive antigen (sick) stat is running about 0.1%, or one in a thousand tests where there is no symptoms. This is now our %infective rate in the general population...…. Today, I saw a lot of people with masks walking along the streets. My wife says she's got one for me. I got one from my doctor. So here you are, in Utah, walking along a practically empty street, wearing your mask, encountering oh,maybe five people each block. You'd have to walk 200 blocks, or 33 miles on average, to pass one covid positive person.....
Taking the numbers given, if plotted on a scale with new cases versus 1 day's time progress, the curve is about two or three weeks past the peak number of cases, but with thousands of tests being done where available, we are now finding a significant number of our new "patients" with the positive antigen testS (sick+) though, perhaps, asymptomatic or probably mild cases.
Here's a report on a survey done with the antibody test..... in Colorado, one of the early hot spots....
https://reason.com/2020/04/17/antib...onfirmed-covid-19-cases-and-total-infections/
The article is written with an unblushing bias to make the worst of the news..... saying 1% or maybe 2% of the general population tested positive. Extrapolating this Denver area survey to the rest of the US, we would have 5M cases nationwide, and 30k cases in Utah..... 7X, 10x reported cases. I might note here that antibody tests will never err on the high side, but are prone to err on the low side, meaning you may not have developed an antibody to the same ligand as the antibody used in the test.... But hey, if you get the positive result, you can be pretty sure of the positive conclusion that you have immunity to the virus.
What this means is that far more people experience mild or no illness from Covid than we knew or expected.
In Utah, over 1% of people on the street have had it, and lived to not know they had it. That's about 30k people. Only 3k have had it at all, and only 2.5% of those died from it, for a death rate of less than one in 1000 Utahns. The probabilt of a positive infectious carrier is really less than 1%, maybe 0.5%
Looks pretty clear we've all been panicked, real good, and probably on purpose. Somebody needs to investigate Dr. Anthony Fauci…… uhhhmmmm…… well, it could be all that heavy drinking Utahns are known for, or the Jacuzzi Lifestyle of Mormonism...… or HCQ being pushed on the dark streets around Pioneer Park.
Sometimes I just hafta laugh.
I see a lot of people getting mad at the nonsense quarantine orders, governors run amok with their decrees. There's gonna be riots as the facts become clear this Great Panic was mostly just the flu.
https://reason.com/2020/04/17/antib...onfirmed-covid-19-cases-and-total-infections/
The article is written with an unblushing bias to make the worst of the news..... saying 1% or maybe 2% of the general population tested positive. Extrapolating this Denver area survey to the rest of the US, we would have 5M cases nationwide, and 30k cases in Utah..... 7X, 10x reported cases. I might note here that antibody tests will never err on the high side, but are prone to err on the low side, meaning you may not have developed an antibody to the same ligand as the antibody used in the test.... But hey, if you get the positive result, you can be pretty sure of the positive conclusion that you have immunity to the virus.
What this means is that far more people experience mild or no illness from Covid than we knew or expected.
In Utah, over 1% of people on the street have had it, and lived to not know they had it. That's about 30k people. Only 3k have had it at all, and only 2.5% of those died from it, for a death rate of less than one in 1000 Utahns. The probabilt of a positive infectious carrier is really less than 1%, maybe 0.5%
Looks pretty clear we've all been panicked, real good, and probably on purpose. Somebody needs to investigate Dr. Anthony Fauci…… uhhhmmmm…… well, it could be all that heavy drinking Utahns are known for, or the Jacuzzi Lifestyle of Mormonism...… or HCQ being pushed on the dark streets around Pioneer Park.
Sometimes I just hafta laugh.
I see a lot of people getting mad at the nonsense quarantine orders, governors run amok with their decrees. There's gonna be riots as the facts become clear this Great Panic was mostly just the flu.
So here is the graph for the flu this year. Peaked in January, went steeply to zero by March, when the Covid stats were increasing....
https://www.cdc.gov/flu/weekly/index.htm
however, before I shine my tin foil hat very much more, the data here is based on actual diagnostic tests for the flu strains, so I'm pretty sure, if these tests were done, the diagnosis would be accurate.
Just a question of presumptions being made on a few symptoms, without a diagnostic test, and how many cases were misdiagnosed without positive evidence.
The answer is assuredly non-zero, maybe 5% or more of the covid stats. who knows, no test done.
https://www.cdc.gov/flu/weekly/index.htm
however, before I shine my tin foil hat very much more, the data here is based on actual diagnostic tests for the flu strains, so I'm pretty sure, if these tests were done, the diagnosis would be accurate.
Just a question of presumptions being made on a few symptoms, without a diagnostic test, and how many cases were misdiagnosed without positive evidence.
The answer is assuredly non-zero, maybe 5% or more of the covid stats. who knows, no test done.